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Cat. No. | Product Name | Target | Signaling Pathways |
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T70484 |
AD-35
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AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β. | |||
T78688 | HPK1-IN-35 | ||
HPK1-IN-35,作为一种选择性的HPK1抑制剂,表现出了3.5 nM的强效IC50。该化合物能够抑制p-SLP76的表达并增强IL-2的分泌。 | |||
T37590 |
ML 3403
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p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively). Laufer et al (2003) Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes. J.Med.Chem. 46 3230 PMID:12852754 |Kammerer et al (2007) Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-... | |||
T38106 |
JC-171
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JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activation and IL-1β production in primary macrophages dose dependently[1]. ... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-04793 |
IL-35 Protein, Human, Recombinant (Flag & His)
NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NF... |
Human | HEK293 Cells |
IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1. | |||
TMPY-03879 |
IL-35 Protein, Human, Recombinant
白介素,P35,NFSK,NKSF1,IL-12A,Interleukin-... |
Human | HEK293 Cells |
IL-35 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 102 kDa and the accession number is P29459-1. | |||
TMPY-06105 |
IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)
P35,interleukin 12A,IL-35,NFSK, |
Human | HEK293 Cells |
IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 102.1 kDa and the accession number is Q14213. | |||
TMPY-04863 |
IL-12 Protein, Human, Recombinant
IMD29,CLMF,IL12,NFSK,白细胞介素,IL-12A,interleu... |
Human | HEK293 Cells |
IL-12 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 57.2 kDa and the accession number is P29459-1&NP_002178.2. | |||
TMPY-00838 |
IL-12A Protein, Human, Recombinant (hFc)
IL-12A,NKSF1,NFSK,CLMF,P35,interleukin 12A |
Human | HEK293 Cells |
IL-12A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is P29459. | |||
TMPY-01409 |
IL-12A Protein, Human, Recombinant (His)
NKSF1,P35,NFSK,IL-12A,interleukin 12A,CLMF |
Human | HEK293 Cells |
IL-12A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P29459. | |||
TMPY-02109 |
IL-12 Protein, Human, Recombinant (His)
IL12,NKSF1,IMD28,CLMF2,白细胞介素,NKSF2,NKSF,CLMF,IMD29,... |
Human | HEK293 Cells |
IL-12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459-1&NP_002178.2. | |||
TMPY-05458 |
IL-12 Protein, Human, Recombinant (His), Biotinylated
NKSF,IL-12A,白细胞介素,白介素,interleukin 12A,IMD29,NFSK,NK... |
Human | HEK293 Cells |
IL-12 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459.2&NP_002178.2. | |||
TMPY-01371 |
IL-17RA Protein, Human, Recombinant (His)
CANDF5,CD217,CDw217,IL-17RA,hIL-17R,IL... |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1. | |||
TMPJ-00594 |
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
Interleukin-13,白细胞介素,IL-13,白介素 |
Human | HEK293 Cells |
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 KDa and the accession number is AAK53823. | |||
TMPY-00755 |
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)
chemokine (C-X-C motif) ligand 8,Interleukin-8,LYNAP,NAP1,NA... |
Human | HEK293 Cells |
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5. | |||
TMPJ-00216 |
IL-12B Protein, Human, Recombinant
Interleukin-12 subunit beta,IL-12B,CLMF p40,NKSF2,I... |
Human | HEK293 Cells |
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells develop... |