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4

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T70484 AD-35

AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
T78688 HPK1-IN-35

HPK1-IN-35,作为一种选择性的HPK1抑制剂,表现出了3.5 nM的强效IC50。该化合物能够抑制p-SLP76的表达并增强IL-2的分泌。
T37590 ML 3403

p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively). Laufer et al (2003) Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes. J.Med.Chem. 46 3230 PMID:12852754 |Kammerer et al (2007) Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-...
T38106 JC-171

JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activation and IL-1β production in primary macrophages dose dependently[1]. ...

化合物

AD-35
Cat.No: T70484
Synonym:
Target:
HPK1-IN-35
Cat.No: T78688
Synonym:
Target:
ML 3403
Cat.No: T37590
Synonym:
Target:
JC-171
Cat.No: T38106
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-04793 IL-35 Protein, Human, Recombinant (Flag & His)

NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NF...

Human HEK293 Cells
IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1.
TMPY-03879 IL-35 Protein, Human, Recombinant

白介素,P35,NFSK,NKSF1,IL-12A,Interleukin-...

Human HEK293 Cells
IL-35 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 102 kDa and the accession number is P29459-1.
TMPY-06105 IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)

P35,interleukin 12A,IL-35,NFSK,

Human HEK293 Cells
IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 102.1 kDa and the accession number is Q14213.
TMPY-04863 IL-12 Protein, Human, Recombinant

IMD29,CLMF,IL12,NFSK,白细胞介素,IL-12A,interleu...

Human HEK293 Cells
IL-12 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 57.2 kDa and the accession number is P29459-1&NP_002178.2.
TMPY-00838 IL-12A Protein, Human, Recombinant (hFc)

IL-12A,NKSF1,NFSK,CLMF,P35,interleukin 12A

Human HEK293 Cells
IL-12A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is P29459.
TMPY-01409 IL-12A Protein, Human, Recombinant (His)

NKSF1,P35,NFSK,IL-12A,interleukin 12A,CLMF

Human HEK293 Cells
IL-12A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P29459.
TMPY-02109 IL-12 Protein, Human, Recombinant (His)

IL12,NKSF1,IMD28,CLMF2,白细胞介素,NKSF2,NKSF,CLMF,IMD29,...

Human HEK293 Cells
IL-12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459-1&NP_002178.2.
TMPY-05458 IL-12 Protein, Human, Recombinant (His), Biotinylated

NKSF,IL-12A,白细胞介素,白介素,interleukin 12A,IMD29,NFSK,NK...

Human HEK293 Cells
IL-12 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459.2&NP_002178.2.
TMPY-01371 IL-17RA Protein, Human, Recombinant (His)

CANDF5,CD217,CDw217,IL-17RA,hIL-17R,IL...

Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1.
TMPJ-00594 IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated

Interleukin-13,白细胞介素,IL-13,白介素

Human HEK293 Cells
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 KDa and the accession number is AAK53823.
TMPY-00755 IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)

chemokine (C-X-C motif) ligand 8,Interleukin-8,LYNAP,NAP1,NA...

Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPJ-00216 IL-12B Protein, Human, Recombinant

Interleukin-12 subunit beta,IL-12B,CLMF p40,NKSF2,I...

Human HEK293 Cells
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells develop...

重组蛋白

IL-35 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-04793
Species: Human
Expression System: HEK293 Cells
IL-35 Protein, Human, Recombinant
Cat.No: TMPY-03879
Species: Human
Expression System: HEK293 Cells
IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)
Cat.No: TMPY-06105
Species: Human
Expression System: HEK293 Cells
IL-12 Protein, Human, Recombinant
Cat.No: TMPY-04863
Species: Human
Expression System: HEK293 Cells
IL-12A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00838
Species: Human
Expression System: HEK293 Cells
IL-12A Protein, Human, Recombinant (His)
Cat.No: TMPY-01409
Species: Human
Expression System: HEK293 Cells
IL-12 Protein, Human, Recombinant (His)
Cat.No: TMPY-02109
Species: Human
Expression System: HEK293 Cells
IL-12 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05458
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His)
Cat.No: TMPY-01371
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00594
Species: Human
Expression System: HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)
Cat.No: TMPY-00755
Species: Human
Expression System: HEK293 Cells
IL-12B Protein, Human, Recombinant
Cat.No: TMPJ-00216
Species: Human
Expression System: HEK293 Cells
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